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We Serving the Health and Biotechnology of Humanity
제품코드 : CSB-RA292183A0HU
제품정보 : Tag Antibody
Description | STAG2 encodes a subunit of the cohesin complex and is one of the most mutated genes in human cancer. STAG2 inactivation has been demonstrated to cause aneuploidy via sister chromatid cohesion, as well as increased DNA damage, which could facilitate further mutagenesis. STAG2 is required for the progression of DNA replication forks. STAG2 deficiency disrupts the interaction of cohesin with the replication machinery, resulting in replication fork stalling and collapse, as well as failure to develop SMC3 acetylation. As a result, STAG2 loss causes synthetic lethality with particular DNA repair ge...Read more | ||||||
Uniprot No. | Q8N3U4 | ||||||
Target Names | STAG2 | ||||||
Alternative Names | Cohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2), STAG2, SA2 | ||||||
Species Reactivity | Human | ||||||
Immunogen | A synthesized peptide derived from human SA2 | ||||||
Immunogen Species | Homo sapiens (Human) | ||||||
Conjugate | Non-conjugated | ||||||
Clonality | Monoclonal | ||||||
Isotype | Rabbit IgG | ||||||
Clone No. | 3H4 | ||||||
Purification Method | Affinity-chromatography | ||||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
Buffer | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | ||||||
Form | Liquid | ||||||
Tested Applications | ELISA, WB, IF | ||||||
Recommended Dilution |
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Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunofluorescence (IF) Protocol | ||||||
Troubleshooting and FAQs | Antibody FAQs | ||||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |