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> 제품정보 > 시약 > 해외 공식 대리점 > [CSB-RA292183A0HU] STAG2 Antibody
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[CSB-RA292183A0HU] STAG2 Antibody

제품코드 : CSB-RA292183A0HU

제품정보 : Tag Antibody

  • WB:1:500-1:5000
  • IF:1:20-1:200

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  • 전화번호
    2292-8870

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Product Details

Description
STAG2 encodes a subunit of the cohesin complex and is one of the most mutated genes in human cancer. STAG2 inactivation has been demonstrated to cause aneuploidy via sister chromatid cohesion, as well as increased DNA damage, which could facilitate further mutagenesis. STAG2 is required for the progression of DNA replication forks. STAG2 deficiency disrupts the interaction of cohesin with the replication machinery, resulting in replication fork stalling and collapse, as well as failure to develop SMC3 acetylation. As a result, STAG2 loss causes synthetic lethality with particular DNA repair ge...Read more
Uniprot No.Q8N3U4
Target NamesSTAG2
Alternative NamesCohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2), STAG2, SA2
Species ReactivityHuman
ImmunogenA synthesized peptide derived from human SA2
Immunogen SpeciesHomo sapiens (Human)
ConjugateNon-conjugated
ClonalityMonoclonal
IsotypeRabbit IgG
Clone No.3H4
Purification MethodAffinity-chromatography
ConcentrationIt differs from different batches. Please contact us to confirm it.
BufferRabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
FormLiquid
Tested ApplicationsELISA, WB, IF
Recommended Dilution
ApplicationRecommended Dilution
WB1:500-1:5000
IF1:20-1:200
ProtocolsELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQsAntibody FAQs
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead TimeBasically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.