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> 제품정보 > 시약 > 해외 공식 대리점 > [1425-050] Human Interferon-gamma, accession # P01579, Gln24-Arg162
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[1425-050] Human Interferon-gamma, accession # P01579, Gln24-Arg162

제품코드 : 1425-050

제품정보 : CellGenix® Recombinant Human IFN-γ reliably promotes the maturation of monocyte-derived dendritic cells (Mo-DCs) and the generation of cytokine induced killer cells (CIK cells). It is produced in our dedicated animal-free GMP facility ensuring maximum saf

  • Produced in our dedicated animal-free facility
  • High purity, activity and product stability

제품문의

  • 전화번호
    2292-8870

제품상세

General Information

Interferon-gamma (IFN-γ) is a cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. It is the only member of the type II class of interferons and is predominantly produced by natural killer cells (NK cells) and T cells.

IFN-γ is used in the cell and gene therapy space for the ex vivo maturation of Mo-DCs, ex vivo generation of CIK cells and stimulation of monocytes, macrophages and microglia.


Technical Details

Source
Expressed in E. coli
Description

Human Interferon-gamma, accession # P01579, Gln24-Arg162

Formulation

Lyophilized from a 0.2 µm-filtered solution containing 20 mM succinate, pH 5.0

Final manufacturing steps and Quality Control (QC) are performed in a GMP facility.

 Preclinical
Molecular weight16.5 kDa
Purity≥ 95% as determined by SDS-PAGE
Activity≥ 10 x 106 IU/mg, calibrated against Imukin® Measured in a cell cytotoxicity assay using HT-29 cells
Endotoxin level< 1000 EU/mg
Intended useIntended for preclinical ex vivo use. Not intended for therapeutic use.

 

Handling Instructions

Reconstitution

Recommended in sterile water to a final concentration of 250 µg/ml.

Shipment

Ambient temperature. Please refer to our Technote Shipment of CellGenix® Preclinical and GMP Cytokines at Ambient Temperatures.

Expiry

3 years from date of shipment.

Storage & Stability

Store lyophilized cytokine at -20°C to -80°C.

Avoid repeated freeze/thaw cycles.