제품상세

Product Name

Stemolecule XAV939

Catalog Number

04-0046

Size

2 mg

AlternateName(s)

2-(4-(trifluoromethyl)phenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol

Chemical Formula

C14H11F3N2OS

Molecular Weight

312.31

CAS Number

284028-89-3

Purity

Greater than 95% by HPLC analysis

Formulation

White powder

Solubility

XAV939 is reported to be soluble in DMSO at 100 mM.

Reconstitution

For a 10 mM concentrated stock solution of XAV939, reconstitute the compound by adding 640.4 µL of DMSO to the entire contents of the vial. If precipitate is observed, warm the solution to 37 °C for 2 to 5 minutes. For use in cell culture, warm the media prior to adding reconstituted compound. Note: for most cells, the maximum tolerance to DMSO is less than 0.5%. 

Storage and Stability

Store powder at −20 °C protected from light. Information about the stability of Stemolecules in solution is largely not available. As a general guideline, we recommend that stock solution be freshly made and stored in aliquots at −20 °C, protected from light. The effect of storage of stock solutions should be verified for each application.

Quality Control

The purity of XAV939 is determined by HPLC analysis. The molecular weight is determined by mass spectrometry. No acute cytotoxicity is observed in mouse embryonic stem cells following a 6 hour exposure to 1 nM — 100 uM of XAV939.