제품상세

Product Name

Stemolecule ALK5 Inhibitor (RepSox)

Catalog Number

04-0015

Size

1 mg

Alternate Name(s)

• RepSox
• E 616452
• SJN 2511
• 2-(3-(6-methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine

Chemical Formula

C17H13N5

Molecular Weight

287.32

CAS Number

446859-33-2

Purity

Greater than 99% by HPLC analysis

Formulation

Yellow solid

Solubility

For a 10 mM concentrated stock solution of ALK5 Inhibitor, reconstitute the compound by adding 348 µL of DMSO to the entire contents of the vial. If precipitate is observed, warm the solution to 37 °C for 2 to 5 minutes. For cell culture, the media should be prewarmed prior to adding the reconstituted compound. Note: for most cells, the maximum tolerance to DMSO is less than 0.5%. This molecule is soluble in DMSO at 100 mM and methanol at 17 mM.

Storage and Stability

Store powder at 4 °C or lower, protected from light. Information about the stability of Stemolecules in solution is largely not available. As a general guideline, we recommend that stock solution be freshly made and stored in aliquots at −20 °C. The effect of storage of stock solutions should be verified for each application.

Quality Control

The purity of ALK5 Inhibitor was determined by HPLC analysis. The accurate mass was determined by mass spectrometry. Cellular toxicity of ALK5 Inhibitor was tested on HeLa and HEK293 cells.