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> 제품정보 > 시약 > 해외 공식 대리점 > [1423-050] Human OSM, accession #P13725, Ala26-Arg221
제품명

[1423-050] Human OSM, accession #P13725, Ala26-Arg221

제품코드 : 1423-050

제품정보 : CellGenix® Recombinant Human OSM promotes the differentiation of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) derived hepatoblasts into hepatocytes. It is produced in our dedicated animal-free GMP facility ensuring maximum safety

  • Produced in our dedicated animal-free facility
  • High purity, activity and product stability

제품문의

  • 전화번호
    2292-8870

제품상세

General Information

Oncostatin M (OSM) is a cytokine belonging to the interleukin-6 (IL-6) subfamily and it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. It is primarily produced by T cells and monocytes. OSM plays an important role in liver development, hematopoiesis, and inflammation, and also has been shown to be associated with bone formation and resorption.


Technical Details

Source
Expressed in E. coli
Description

Human OSM, accession #P13725, Ala26-Arg221

Formulation

Lyophilized from a 0.2 µm-filtered solution in PBS

Final manufacturing steps and Quality Control (QC) are performed in a GMP facility.

 Preclinical
Molecular weight22.1 kDa
Purity≥ 95% as determined by SDS-PAGE
Activity> 40 x 106 IU/mg, calibrated against NIBSC #93/564 Cell proliferation assay using a human factor dependent cell line, TF-1 
Endotoxin level< 1000 EU/mg
Intended useIntended for preclinical ex vivo use. Not intended for therapeutic use.


 

Handling Instructions

Reconstitution

Recommended in sterile water to a final concentration of 250 µg/ml.

Shipment

Ambient temperature. Please refer to our Technote Shipment of CellGenix® Preclinical and GMP Cytokines at Ambient Temperatures.

Expiry

3 years from date of shipment.

Storage & Stability

Store lyophilized cytokine at -20°C to -80°C.

Avoid repeated freeze/thaw cycles.