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홈 > 제품정보 > 시약 > 해외 공식 대리점 > [1406-010] Human TNF-α, accession # P01375, Val77-Leu233
[1406-010] Human TNF-α, accession # P01375, Val77-Leu233
제품코드 : 1406-010
제품정보 : CellGenix® Recombinant Human TNF-α reliably stimulates the maturation of immature dendritic cells (DCs). CellGenix® rh TNF-α is produced in our dedicated animal-free GMP facility ensuring maximum safety for optimal use in ATMP manufacturing.
- Produced in our dedicated animal-free facility
- Compliant to USP Chapter <1043> and Ph. Eur. General Chapter 5.2.12 (GMP)
- FDA Drug Master File available (GMP)
제품문의
-
- 전화번호
- 2292-8870
- 이메일
- dreamcell@dreamcell.co.kr
제품상세
General Information
Tumor necrosis factor alpha (TNF-α) is a cytokine that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism. It is mainly produced by monocytes and macrophages as a response to infection, injury, or tumor burden. TNF-α can also be produced from a range of other cell types such as T cells, natural killer cells (NK cells) and neutrophils.
CellGenix® TNF-α is used in the cell and gene therapy space for the ex vivo maturation of immature DCs.
Technical Details
Source
Expressed in E. coli
Description
Human TNF-α, accession # P01375, Val77-Leu233
Formulation
Lyophilized from 200 µl of a 0.2 µm-filtered solution containing 1.5 mM potassium phosphate, 8.1 mM sodium phosphate, 2.7 mM potassium chloride and 137 mM sodium chloride, pH 7.5
Both product grades are produced under the same conditions in a GMP facility, ensuring an equal product quality and performance. We offer a more comprehensive QC testing including tighter specifications and documentation for our GMP products: Preclinical vs GMP.
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Handling Instructions
Reconstitution
Recommended in sterile water to a final concentration of 250 µg/ml.
Shipment
Ambient temperature. Please refer to our Technote Shipment of CellGenix® Preclinical and GMP Cytokines at Ambient Temperatures.
Expiry
≥ 6 months from date of shipping. Please refer to Certificate of Analysis for the exact expiry date.
Storage & Stability
Store lyophilized cytokine at -20°C to -80°C.
Store a 100 µg/ml reconstituted cytokine solution:
• 4 weeks at 2°C to 8°C under sterile conditions after reconstitution. Store in the original container.
• 4 months at -20°C to -80°C under sterile conditions after reconstitution. Store in 60 µl aliquots in polypropylene cryogenic vials.
Avoid repeated freeze/thaw cycles.